Inhibition of Na,K-ATPase by a new ATP analog, adenosine-5-N′-(2,4-dinitro-5-fluorophenyl)phosphohydrazide
نویسندگان
چکیده
منابع مشابه
Inhibition by Adenosine 5'-Triphosphate
Two major species of glucose-6-phosphate dehydrogenase (EC 1.1.1.49) differing in size, pyridine nucleotide specificity, and susceptibility to inhibition by adenosine 5'-triphosphate (ATP) were detected in extracts of Pseudomonas multivorans (which has recently been shown to be synonymous with the species Pseudomonas cepacia) ATCC 17616. The large species (molecular weight ca. 230,000) was acti...
متن کاملSpecific synthesis of adenosine(5')tetraphospho(5')nucleoside and adenosine(5')oligophospho(5')adenosine (n > 4) catalyzed by firefly luciferase.
Luciferase catalyzes the preferential synthesis of adenosine(5')tetraphospho(5')nucleoside (Ap4N) in the presence of luciferin (LH2), adenosine 5'-[gamma-thio]triphosphate (ATP[gamma S]) and NTP (other than ATP), with very low, or undetectable synthesis of Ap4A or Np4N, because ATP[gamma S] is a good adenylyl donor for the formation of the E-LH2-AMP complex, but a poor adenylyl acceptor from th...
متن کاملRole of adenosine triphosphate (ATP) and NaK ATPase in the inhibition of proximal tubule transport with intracellular cystine loading.
Cellular cystine loading with cystine dimethyl ester inhibits volume absorption, transepithelial potential difference, glucose transport, and bicarbonate transport in proximal convoluted tubules perfused in vitro. This study examined the roles of ATP and NaK ATPase in this in vitro model of the Fanconi syndrome of cystinosis. Intracellular ATP was measured using the luciferin-luciferase assay. ...
متن کاملAdenosine 5′-triphosphate (ATP) synthesis by oxidative phosphorylation or photophosphorylation
phosphorylation or photophosphorylation is a multi-step, membrane-located process that provides the bulk of cellular energy in eukaryotes and many prokaryotes. Most of the ATP synthesis in these cells is catalyzed by the enzyme, F1Fo-ATP synthase, also called F1Fo-ATPase (F-ATPase), which in its simplest, bacterial, form is composed of eight subunits (α3:β3:γ:δ:ε:a:b2:c9–12). The archaeal A1Ao-...
متن کاملInhibition of glucose 6-phosphate dehydrogenase by adenosine 5'-triphosphate.
D-glucose 6-phosphate dehydrogenase (G6PDH) catalyzes the oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconate-6-lactone and thereby constitutes the step which introduces hexoses into the "pentose cycle" pathway. This well-known enzyme, which is widely distributed in nature, was purified to varying degrees from different sources (for literature see refs. 1 and 2). The yeast enzyme,3 4 w...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1991
ISSN: 0014-5793
DOI: 10.1016/0014-5793(91)80483-j